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Ilosone (erythromycins) is used to treat many kinds of infections. Erythromycins are also used to prevent ''strep'' infections in patients with a history of rheumatic heart disease who may be allergic to penicillin.

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Uses

Erythromycin is an antibiotic used to treat a wide variety of bacterial infections. This antibiotic only treats bacterial infections. It will not work for viral infections (e.g., common cold, flu). Unnecessary use or overuse of any antibiotic can lead to its decreased effectiveness. These medicines may also be used to treat Legionnaires' disease and for other problems as determined by your doctor. They will not work for colds, flu, or other virus infections.

How to take

This medication may be taken with food or milk if stomach upset occurs. Antibiotics work best when the amount of medicine in your body is kept at a constant level. Do this by taking the medication at evenly spaced intervals throughout the day and night. Continue to take this medication until the full prescribed amount is finished even if symptoms disappear after a few days. Stopping the medication too early may allow bacteria to continue to grow resulting in a relapse of the infection.

Side effects

May cause stomach upset, diarrhea, loss of appetite, nausea, vomiting and stomach cramps the first few days as your body adjusts to the medication. If these symptoms persist or become severe, inform your doctor. In addition to the above side effects, erythromycin estolate rarely causes dark urine, pale stools, severe stomach pain, unusual tiredness and weakness or yellow eyes and skin. Be sure to contact your doctor if these symptoms should occur. In the unlikely event you have an allergic reaction to this drug, seek medical attention immediately. Symptoms of an allergic reaction include rash, itching, swelling, dizziness, trouble breathing. If you notice other effects not listed above, contact your doctor or pharmacist.

Precaution

Tell your doctor your medical history, especially of liver disease/jaundice, allergies. Use of this medication for prolonged or repeated periods may result in a secondary infection (e.g., oral, bladder or vaginal yeast infection) Caution is advised when this drug is used in infants. Though very unlikely to happen, a stomach problem called IHPS (infantile hypertrophic pyloric stenosis) has been noted. Contact your child's doctor immediately if the child has persistent vomiting or increased irritability. This drug should be used only if clearly needed during pregnancy. Small amounts of drug do appear in breast milk, so consult your doctor before breast-feeding

Avoid exposure to sunlight or artificial UV rays (sunlamps or tanning beds). Erythromycin can make your skin more sensitive to sunlight and sunburn may result. Use a sunscreen (minimum SPF 15) and wear protective clothing if you must be out in the sun.
Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or has blood in it, call your doctor. Do not use any medicine to stop the diarrhea unless your doctor has told you to.

Drug interactions

Tell your doctor of all the drugs you may use, (prescription and nonprescription), especially of the following: carbamazepine, cyclosporine, theophylline, certain benzodiazepines (e.g., midazolam, triazolam), warfarin, felodipine (a calcium channel blocker), cisapride, birth control pills, corticosteroids (e.g., prednisone), digoxin, certain live vaccines, disopyramide, phenytoin, all other antibiotics, certain "statin" drugs used for high cholesterol (e.g., atorvastatin, lovastatin, simvastatin). This drug may interfere with the effectiveness of birth control pills. Discuss using other methods of birth control with your doctor. Other drugs besides erythromycin which may affect the heart rhythm (QTc prolongation in the EKG) include dofetilide, pimozide, quinidine, sotalol, procainamide, and sparfloxacin among others. QTc prolongation can infrequently result in serious, rarely fatal, irregular heartbeats. Consult your doctor or pharmacist for details. Ask for instructions about whether you need to stop any other QTc-prolonging drugs you may be using in order to minimize the risk of this effect. Do not start or stop any medicine without doctor or pharmacist approval.

Missed dose

If you miss a dose, take as soon as remembered; do not take if it is almost time for the next dose, instead, skip the missed dose and resume your usual dosing schedule. Do not "double-up" the dose to catch up.

Storage

Store at room temperature between 59 and 86 degrees F (between 15 and 30 degrees C) away from moisture and sunlight. Do not store in the bathroom. Keep away from children and pets.